Professor of Surgery
freemanb@wustl.edu

Our research focus is dedicated to understanding participant preferences and concerns regarding research participation in the context of critical illness. Our hope is that the insights gained from these investigations will serve to facilitate the conduct of clinical investigations in the emergent setting while insuring rigorous patient safeguards.

• Freeman BD, Danner RL, Banks S, Natanson C: Safeguarding patients in clinical trials with high mortality rates, American Journal of Respiratory and Critical Care Medicine, Vol 164. Pp 190-192, 2001.
• Freeman BD, Kennedy CR, Frankel HL, Clarridge BR, Bolcic-Jankovic D, Iverson E, Shehane E, Celious A, Zehnbauer BA, Buchman TG: Ethical considerations in the collection of genetic data from critically ill patients – what do published studies reveal about potential directions for empirical research? Pharmacogenomics Journal (10:77-85;2010).
• Freeman BD, Kennedy CR, Bolcic-Jankovic D, Eastman A, Iverson E, Shehane E, Celious A, Barillas J, Clarridge B: Brief Report: Considerations in the construction of a quantitative instrument to assess attitudes regarding critical illness genetic variation research; Journal of Empirical Research in Human Research Ethics; 2012;7:1:58-70.
• Iverson E, Celious A, Kennedy CR, Shehane E, Eastman A, Warren V, Bolcic-Jankovic D, Clarridge B, Freeman BD. Real-time perspectives of surrogate decision makers regarding critical illness research – findings of focus group participants. Chest. 2012;142(6):1433-1439.
• Iverson E, Celious A, Kennedy CR, Shehane E, Eastman A, Warren V, Freeman BD. Perspectives of surrogate decision makers for critically ill patients regarding gene variation research, Genetics in Medicine 15(5), 368-373; 2013.